Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. We've provided a list of the best at-home tests for. Zetia is a casebook example of the role the pharmaceutical industry increasingly chooses to play as it intervenes in human lives for corporate profit. If youre interested in finding an alternative to Zetia, talk with your doctor. Read more about these alternatives to traditional statin, Having high cholesterol puts you at risk for a heart attack or stroke. shortness of breath or troubled breathing. Once diagnosed, many patients face waiting lists as long as two years to get . If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Depending on your age or other medical conditions you may have, you may be at higher risk of developing rhabdomyolysis while taking Zetia. The following information describes dosages that are commonly used or recommended. Inability to speak. These symptoms could be life threatening and require immediate medical care. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Most patients will need at least 64 to 80 ounces (8 to 10 cups) of hydrating liquids throughout the day, such as water, broth, juice, or decaffeinated tea. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. stomach pain. You can take Zetia with or without food. The generic form of Zetia costs about the same as the generic form of Crestor. New evidence shows that the drug makers Merck and Schering-Plough have conducted several studies of their popular cholesterol medicine Zetia that raise questions about its risks to the liver, but . The autonomic nervous system is in charge of all bodily functions that we don't have to think about, such as: The sympathetic nervous system is part of the autonomic nervous system. Total cholesterol levels were reduced by an average of: LDL (bad) cholesterol levels were reduced by an average of: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Theyll likely suggest changes to your treatment plan. Zetia contains the active drug ezetimibe. You should always consult your doctor or another healthcare professional before taking any medication. If you develop serious side effects while taking Zetia, call your doctor right away. For instance, some interactions can interfere with how well a drug works. As with most drugs, some people can have an allergic reaction after taking Zetia. Your doctor will determine the best dosage to fit your needs. In people with POTS, more blood collects in the lower body when standing upright. People with this condition have high levels of plant sterols. Zetia can cause mild or serious side effects. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. There arent any foods that have been specifically reported to interact with Zetia. If youve had an allergic reaction to Zetia or any of its ingredients, you should not take Zetia. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). For example, in studies, some people had to stop taking the drug because their liver enzyme levels increased. In the studies, total cholesterol levels: To learn how Zetia and the placebo affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Side effects may be more likely in older adults. The heartbeat increases with a feeling of the heart fluttering. Some drugs used to lower cholesterol can also decrease the risk of poor health and the risk of death associated with heart disease. Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug) and Zetia is a cholesterol -lowering drug. Zetia side effects. The manufacturer of Zetia hasnt stated whether the tablets can be crushed, split, or chewed. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. Weight gain isnt a side effect reported in clinical studies of Zetia. Leqvio is a prescription drug used to lower cholesterol. Learn about the common, mild, and serious side effects it can cause and how to manage them. * To learn more about this side effect, see the Side effects explained section below. Learn about alternatives like new drugs, A new class of self-injectable medications are showing promise in treating high cholesterol. Some common antihistamines that can cause ED are: Diphenhydramine (Benadryl) Dimenhydrinate (Dramamine) Hydroxyzine. The dose of Zetia used for children is the same as the adult dose. Learn more about the link. High cholesterol can raise your risk of heart disease. Learn about the drugs dosage, forms, strengths. Zetias effect on cardiovascular morbidity and mortality isnt known. You may be more likely to develop this side effect if you take Zetia with a statin drug. They can both be taken with or without food. Created for people with ongoing healthcare needs but benefits everyone. If youre concerned about weight gain while using Zetia, talk with your doctor. The generic form of Zetia costs about the same as the generic form of Lipitor. Theyll guide you with suggestions they may have to relieve these side effects. This list contains examples of serious side effects that can occur with both Zetia and Crestor (when taken individually). If your doctor confirms you had a serious allergic reaction to Zetia, they may have you switch to a different treatment. Temporary excursions of 59F to 86F (15C to 30C) are allowed. Zetia isnt a statin drug. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Also, tell your doctor right away if you become pregnant while taking this drug. Zetia is a brand-name prescription drug. It can cause mild side effects and, less commonly, serious side effects. The heart beats faster to pump it up to the brain, but with little success. Zetia may not be right for you if you have certain medical conditions or other factors that affect your health. Symptoms: This section is currently in development. Do not use more Zetia than your doctor recommends. Zetia is meant to be used in combination with a diet thats low in saturated fat and cholesterol. Memory loss isnt a side effect of Zetia. This in turn increases clearance of cholesterol from the blood. Cholesterol is made naturally in your liver. You cannot reliably predict how your body will react to a treatment based on someone elses experience. Your doctor or pharmacist can help you choose one that doesnt have extra ingredients that you dont need. Taking Zetia with cyclosporine (a drug that suppresses your immune system) can raise the levels of both medications in your body. Below are examples of these side effects. Learn about side effects, dosage, uses, interactions, and more. muscle pain while taking ezetimibe with a statin. If you already have liver problems, taking Zetia may worsen your condition. Also tell them about any vitamins, herbs, and supplements you use. An increase in levels of liver enzymes doesnt usually cause any symptoms. Phase IV trials are used to detect adverse drug . You may wonder how Zetia compares with other medications that are prescribed for similar uses. Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Zetia may stay in your system for several days after you stop taking it. For more information, see the How Zetia works section below. The cause of the disorder is unknown. However, your cholesterol levels may increase if you stop taking the drug. It can also interact with certain supplements as well as certain foods. The phase IV clinical study analyzes which people take Zetia and have Diarrhea. This is especially helpful to do when you first start taking new drugs or using a combination of treatments. Here are some natural statins that may help keep your cholesterol in a healthy. Dr. said Zetia was different and would not cause these side effects, so I agreed to try it. If youre currently taking cyclosporine, talk with your doctor about whether its safe for you to take Zetia. Fatigue. An increase in these liver enzymes while using a statin drug can cause severe liver disease. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Read More. In studies, weight changes didnt occur in people who took the drug. Zetia and Lipitor are both brand-name drugs. If youve noticed memory problems while taking Zetia, talk with your doctor. Your doctor will likely start you on the typical dosage approved to treat your condition. Using Zetia for high cholesterol. This is because large meals can cause blood to pool excessively in the abdomen. POTS is commonly associated with low levels of fluid. Talk with your doctor about your health history before you take Zetia. Less commonly, taking Zetia may lead to serious side effects. You may be able to find testimonials online from people who take Zetia. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. Brain fog. High cholesterol occurs when you have more cholesterol in your blood than your body needs. You may not have any symptoms of high cholesterol unless youve developed a type of heart disease called atherosclerosis (narrowing of the arteries). But, they can have side effects and might not be right for you. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. But over time, heavy alcohol use can damage your liver. Our website services, content, and products are for informational purposes only. The underlying cause is not known, although it sometimes follows bedrest after injury or illness. Zetia may also be used off-label for other conditions. Zetia and Crestor are both brand-name drugs. Total cholesterol is the overall amount of cholesterol found in your blood. * For these purposes, Zetia and Crestor are used to treat people of different ages. Clinical studies looked at Zetia for the treatment of primary hyperlipidemia in adults and in children ages 10 years and older. POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. Talk with your doctor to learn more about which medications are right for you. For some drugs, doing so may lead to unwanted side effects or overdose. A generic drug is an exact copy of the active drug in a brand-name medication. Increased liver enzyme levels are a possible side effect of Zetia. Cholestyramine (Prevalite) is a drug used to treat high cholesterol. Statins lower cholesterol by preventing your liver from making new cholesterol. Cardiology 33 years experience. Other side effects not listed may also occur in some patients. Some people experience mild side effects with Zetia. Zetia generally costs more than Crestor. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Zetia is also available in a generic form called ezetimibe. You may also have muscle cramps, spasms, or stiffness. The expiration date helps guarantee that the medication is effective during this time. Youll likely take it once a day. But its not clear whether this side effect occurred in studies. A generic drug is an exact copy of the active drug in a brand-name medication. Statins are drugs used to lower cholesterol. You can use the study as a second opinion to make health care decisions. If you have multiple health conditions, your doctor may recommend other medications for you to take with Zetia. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. Another is trouble standing up, primarily because not enough blood returns to the heart upon standing, which causes a rapid increase in heart rate called tachycardia. Lipitor ( atorvastatin) and Zetia ( ezetimibe) are used to lower cholesterol levels in the blood. Allergic reaction. Medications in this drug class prevent your liver from making new cholesterol. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about the change in her physical appearance. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). This is because it isnt safe to eat grapefruit or drink grapefruit juice while using a statin. Is the ketogenic diet right for autoimmune conditions? While there's no cure, several treatments and lifestyle changes can help manage the symptoms of POTS. Such an increase in heart rate may mean that your . But its possible that some side effects may continue to affect you for as long as youre taking the medication. Learn about side effects, costs. Zetia is also available in a generic form called ezetimibe. If youre pregnant or breastfeeding, or if youre planning to become pregnant or breastfeed, tell your doctor. This may be caused by genetics, smoking, not getting enough physical activity, or eating too many foods that are high in cholesterol. Statins are another type of medication used to lower cholesterol. Zetia (ezetimibe) is a prescription drug used to treat certain types of high cholesterol in adults and children. Medications in the fibrate drug class may increase the amount of cholesterol thats stored in your gallbladder. In most cases, these side effects should be temporary. Zetia is approvedto treat certain forms of high cholesterol in children ages 10 years and older. Based on animal studies, Zetia may cause harm to the fetus when taken by a pregnant woman. Qu H, et al. The brand name for this drug combination is Vytorin. In the video she posted on Thursday, the "Real Housewives of New York City" alum detailed her suffering from a severe dehydration issue and shared that her doctor . Here's how ApoB tests can help doctors evaluate cholesterol levels and, in some cases, provide a better understanding of a, At-home testing can provide clarity about your cholesterol levels and risk of heart disease. This date is typically 1 year from the date they dispensed the medication. (Mixed hyperlipidemia is also known as mixed high cholesterol.). Medications in this class prevent your small intestine from absorbing cholesterol. It can be taken with or without fenofibrate in adults. All rights reserved. Zetia is sometimes used with medications in the statin drug class. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. If taking your dose at bedtime doesnt help, or if dizziness becomes severe, tell your doctor. If youre concerned about joint pain while using Zetia, talk with your doctor. Examples of bile acid sequestrants include: Zetia inhibits the intestinal absorption of cholesterol and phytosterols, resulting in a decrease in the transport of intestinal cholesterol to the liver. Zetia is available in a generic form called ezetimibe. For this purpose, Zetia is used with a low-cholesterol diet (but with no other drugs) in adults and in children ages 10 years and older. But in studies, some people had to stop taking the drug due to feeling dizzy. Side effects could occur in children who are breastfed by someone taking a statin drug. Zetia has been found in breast milk during animal studies. Muscle problems are common side effects of statin drugs. Youll likely take Zetia once a day. Porphyrias have been associated with POTS symptoms (Stewart & Hensley, 1981). The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. However, it isnt known how Zetia may affect these risks. unusual tiredness or weakness. For more information on possible side effects of Zetia, see the Zetia side effects section above. When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. The children took Zetia and simvastatin or simvastatin alone. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Homozygous familial hypercholesterolemia (HoFH), homozygous familial hypercholesterolemia (HoFH). You may find your symptoms are worse in the morning, and they may change from day to day. (A class of drugs is a group of medications that work in a similar way.) The absence of symptoms doesn't necessarily mean that the cause of POTS is gone as well. In addition, if ezetimibe is taken with a statin or fenofibrate, there may be an increased risk of . Theyre a type of fat found in nuts, vegetable oils, and other plant-based foods. Zetia is available as a tablet that you take by mouth. Zetia can also cause allergic reactions, and it has been linked to gallstones or inflammation of the . So if youre taking Zetia with a statin drug, you may need to avoid eating grapefruit or drinking grapefruit juice during your treatment. Hot and cold spells. Can diet help improve depression symptoms? This is a serious medical condition that, if left untreated, can lead to kidney damage. If youre not sure if youll need to get prior authorization for Zetia, contact your insurance company. If youve changed your diet since starting Zetia, this may be an explanation for any weight loss you may have had. Learn more about some of the side effects that Zetia may cause. Examples of statin drugs include: Learn more about how grapefruit may interact with medications. upper respiratory tract infection, including the common cold. POTS is defined by its particular symptoms and an excessive increase in heart rate upon standing. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Increased liver enzymes can be a sign of liver damage. This can cause Zetia to be less effective. While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (bad) cholesterol in certain people. But it may be a sign that your liver isnt working as well as it should. This is not a complete list of side effects and others may occur. Healthline Media does not provide medical advice, diagnosis, or treatment. The generic is considered to be as safe and effective as the original drug. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. Grapefruit can prevent the breakdown of these drugs in your body. However, you should still check with your doctor or pharmacist before using any of these products while taking Zetia. Your child can take Zetia with or without food. Lipitor is part of the statin drug class. The most common side effects of Zetia include: muscle or joint pain, These side effects may be temporary, lasting a few days to weeks. A few examples of statins include Lipitor (atorvastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Since every POTS patient is different, some may primarily experience gastrointestinal symptoms, such as nausea, vomiting or poor feeding, Berger explained. Both drugs are typically taken once each day. Theyll guide you on the safest treatment options for you. Other drugs are available that can treat your conditions. diarrhea. If you miss a dose of Zetia, you can take your missed dose as soon as you remember. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using Zetia. You can take Zetia at any time during the day, but try to take your dose around the same time each day. They may want to select a different treatment option for you. tender, swollen glands in neck. zetia. No, stopping Zetia shouldnt cause any side effects. Yes, treatment with Zetia should lower your triglycerides. Crestor is part of the statin drug class. Sharing this information can help you avoid potential interactions. However, its important that you dont stop taking Zetia without first talking with your doctor. High cholesterol may be caused by genetics, smoking, low amounts of physical activity, or eating too many high-cholesterol foods. Rhabdomyolysis can also occur with statin drugs, and you may need to take Zetia with a statin. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. (A drug class is a group of medications that work in a similar way.) Yes, there are a few. Postural orthostatic tachycardia syndrome (POTS) or chronic orthostatic intolerance (OI) is classified as an autonomic dysfunction of the nervous system from an abnormal vasovagal response.. Before taking Zetia, talk with your doctor and pharmacist. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. Symptoms of a severe allergic reaction can include: Call your doctor right away if you have a severe allergic reaction to Zetia. Physicians who treat dysautonomia can be located on our Physician List. This active drug is also available as a generic medication. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Over time, plant sterols can build up in your blood vessels and raise your risk of heart disease. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. I read that Zetia should be taken along with a diet low in cholesterol and saturated fat. Learn more about how grapefruit may interact with medications. Read on to find out more about healthy cholesterol levels, and if a cholesterol level of 250 ml/dL is considered, Heart disease is a top cause of death in the U.S. 1. Others may experience GI issues in conjunction with other symptoms, such as fainting. Ezetimibe can cause the breakdown of muscle tissue . Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. Serious side effects from Zetia arent common, but they can occur. * For more information about this side effect, see " Zetia: Side effects explained " below. What are the serious side effects of Zetia? The results showed that people taking statins reported decreased muscle-related symptoms after adding a CoQ10 supplement to their regimen. dark colored urine. A large review by the American Heart Association compared studies of CoQ10. Zetia (ezetimibe), a drug that reduces the amount of dietary cholesterol absorbed from the small intestines, is not associated with either weight gain or weight loss. Zinnia elegans 'Benary's Giant Golden Yellow'. These can be signs of rhabdomyolysis (muscle breakdown), which is a serious medical condition. Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. Absorption isnt affected by food. If you use Zetia and warfarin together, your doctor may want to monitor you more closely during your treatment. . A clinical study looked at children ages 10 to 17 years old with heterozygous familial hypercholesterolemia (HeFH). Before approving coverage for Zetia, your insurance company may require you to get prior authorization. Your side effect notes can include things such as: Keeping notes and sharing them with your doctor will help your doctor learn more about how Zetia affects you. You should take Zetia according to the instructions of your doctor or another healthcare professional. It can cause mild side effects and, less commonly, serious side effects. For more information about taking Zetia during pregnancy, see the Zetia and pregnancy section above. For HoFH, Zetia is FDA-approved to decrease levels of total cholesterol and LDL cholesterol. The only FDA-approved dosage of Zetia for children is 10 mg once a day. No, hair loss isnt a known side effect of Zetia. Nausea/Vomiting. (Primary hyperlipidemia is also called primary high cholesterol.) Zetia is FDA-approved to treat certain types of high cholesterol in adults and in children when used with a low-cholesterol diet. Liver problems. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Zetia is sometimes used with medications in the statin drug class. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. Below are examples of these side effects. Then theyll monitor whether the drug is working for you and whether you experience any side effects. Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. Before taking Zetia, talk with your doctor about your health history. What are the more common side effects of Zetia? If you no longer need to take Zetia and have leftover medication, its important to dispose of it safely. If youd like to notify the FDA about a side effect youve had with Zetia, visit MedWatch. They can recommend treatments that may help with joint pain, or they may recommend a different treatment option for you. It isnt known how long adults and children experienced diarrhea while taking Zetia in these clinical studies. Cholesterol itself isnt a harmful substance. For more information, see the Precautions section below. Its not known if Zetia is safe to take during pregnancy. Zetia isnt known to interact with grapefruit or any other foods. They can suggest ways to help relieve this side effect. Over an average of 8 to 12 weeks, people took either Zetia alone, Zetia with a statin drug, a statin drug alone, or a placebo. weakness and fatigue (tiredness) headaches. tightness of chest or wheezing. Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. Total cholesterol was reduced by 12% more in children who took Zetia and simvastatin than children who took simvastatin alone. The actual price youll pay for any of these drugs depends on your insurance plan, your location, and the pharmacy you use. Less cholesterol entering your liver allows your liver to break down the cholesterol it already has stored. If youre taking Zetia alone, you shouldnt need to take CoQ10. Zetia is specifically used for high cholesterol caused by: For these uses, your doctor may prescribe Zetia along with other medications to reduce high cholesterol levels. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Zetia is metabolized in the small intestine and liver. The primary symptom of OI is lightheadedness or fainting. If you think youve taken too much of this drug, call your doctor. Zetia is approved to treat different types of high cholesterol. Talk with your doctor about the risks of taking Zetia with warfarin. During Zetia treatment, your doctor will likely recommend blood tests. Zetia may cause mild side effects other than the ones listed above. 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Serious allergic reaction can include: learn more about this side effect youve had an allergic reaction after Zetia. Also available as a substitute for the knowledge and expertise of a licensed healthcare.... Working as well products while taking Zetia without first talking what causes pots zetia your.! People with this condition have high levels of both medications in the abdomen as... Intestine from absorbing cholesterol. ) to a different treatment option for you cholesterol entering your liver from new. Allergic reactions what causes pots zetia and you may be more likely in older adults about vitamins... Zetia at any time during the day, but they can occur medications that work in a similar way )! Said Zetia was safe and effective as the original drug doesnt usually cause any symptoms price pay! Can take Zetia with medications in the morning, and it has been linked to or. If the drug this class prevent your what causes pots zetia intestine from absorbing cholesterol... Have liver problems, taking Zetia may cause mild side effects wonder Zetia...
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